P4107

Sigma

 

[Leu31, Pro34]-Peptide YY

≥95%

Amino Acid Sequence:Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
Linear Formula:C195H296N54O56
Molecular Weight:4292.76
MDL number:MFCD00678656

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Description

Biochem/physiol ActionsAgonist at Y1, Y4, and Y5 NPY receptors.

Properties

assay≥95%
Gene Informationhuman ... PYY(5697)
storage temp.−20°C

Safety

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany3

References

referenceGobbi, M., et al., Autoradiographic reevaluation of the binding properties of 125I-[Leu31,Pro34]peptide YY and 125I-peptide YY3-36 to neuropeptide Y receptor subtypes in rat forebrain. J. Neurochem. 72, 1663, (1999) Abstract
 Dumont, Y., et al., Potent and selective tools to investigate neuropeptide Y receptors in the central and peripheral nervous systems: BIB03304 (Y1) and CGP71683A (Y5). Can. J. Physiol. Pharmacol. 78, 116, (2000) Abstract
 Ferrier, L., et al., Pathways and receptors involved in peptide YY induced contraction of rat proximal colonic muscle in vitro. Gut 46, 370, (2000) Abstract